Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644082 | 0.83 | ALDH1A1 (0.37) | RXFP1POLBMAPT | |
| SCHEMBL8647858 | 0.81 | KMT2A (0.40) | RXFP1CYP1A2CYP2D6GGPS1PDE3B | |
| SCHEMBL8644342 | 0.69 | RXFP1 (0.39) | RXFP1PRNPPDE3BPDE3AEGFR | |
| SCHEMBL8644436 | 0.66 | MMP1 (0.44) | — | |
| SCHEMBL30932231 | 0.65 | PIK3CG (0.46) | CYP1A2POLBMAPT | |
| SCHEMBL9700727 | 0.65 | PIK3CG (0.46) | CYP1A2POLBMAPT | |
| SCHEMBL11764141 | 0.65 | PGK1 (0.39) | — | |
| SCHEMBL9700960 | 0.63 | MAPT (0.35) | RXFP1EGFRHRH4MAPT | |
| SCHEMBL9740990 | 0.63 | MAPT (0.35) | RXFP1EGFRHRH4MAPT | |
| SCHEMBL20156407 | 0.62 | PIK3CG (0.40) | RXFP1PDE3BPDE3AHRH4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710139-A | Heterocyclic compounds | ASTRA AB (SE) | 1998-01-20 | — | — | US | disclosed |
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |