Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8647235 | 0.97 | TDP1 (0.49) | TDP1KMT2ACTDSP1MDM2ELANE | |
| SCHEMBL8646569 | 0.82 | TDP1 (0.43) | TDP1KMT2ACTDSP1MDM2CA12 | |
| SCHEMBL8643783 | 0.82 | TDP1 (0.43) | TDP1KMT2ACTDSP1MDM2NPC1 | |
| Hydrochloric Acid SCHEMBL8648190 | 0.81 | TDP1 (0.43) | TDP1KMT2ACTDSP1MDM2NPC1 | |
| Hydrochloric Acid SCHEMBL8647131 | 0.81 | TDP1 (0.43) | TDP1KMT2ACTDSP1MDM2CA12 | |
| SCHEMBL8651129 | 0.80 | TDP1 (0.42) | TDP1KMT2ACTDSP1MDM2CA12 | |
| SCHEMBL8644541 | 0.80 | ACHE (0.46) | TDP1KMT2ACTDSP1MDM2 | |
| Hydrochloric Acid SCHEMBL8644143 | 0.79 | TDP1 (0.41) | TDP1KMT2ACTDSP1MDM2CA9 | |
| Hydrochloric Acid SCHEMBL8646984 | 0.79 | ACHE (0.46) | TDP1KMT2ACTDSP1MDM2 | |
| SCHEMBL8645472 | 0.75 | DRD2 (0.42) | TDP1KMT2ACA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |