Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8647131 | 0.99 | TDP1 (0.43) | TDP1MC4RCTDSP1SIGMAR1MDM2 | |
| SCHEMBL8644361 | 0.82 | TDP1 (0.51) | TDP1CTDSP1MDM2KMT2AFBP1 | |
| Ethylene SCHEMBL8647235 | 0.80 | TDP1 (0.49) | TDP1CTDSP1MDM2KMT2AFBP1 | |
| SCHEMBL8643783 | 0.77 | TDP1 (0.43) | TDP1CTDSP1MDM2KMT2A | |
| Hydrochloric Acid SCHEMBL8648190 | 0.76 | TDP1 (0.43) | TDP1CTDSP1MDM2KMT2A | |
| SCHEMBL8644541 | 0.76 | ACHE (0.46) | TDP1CTDSP1MDM2KMT2AACHE | |
| SCHEMBL8651129 | 0.76 | TDP1 (0.42) | TDP1CTDSP1MDM2KMT2AFBP1 | |
| Hydrochloric Acid SCHEMBL8644143 | 0.75 | TDP1 (0.41) | TDP1CTDSP1MDM2KMT2AFBP1 | |
| Hydrochloric Acid SCHEMBL8646984 | 0.75 | ACHE (0.46) | TDP1CTDSP1MDM2KMT2AACHE | |
| SCHEMBL8649409 | 0.70 | MC4R (0.41) | MC4RSIGMAR1KMT2AACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |