Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 7/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648847 | 0.88 | BTN3A1 (0.42) | BTN3A1PRTN3TAS1R3TAS1R1ANPEP | |
| SCHEMBL8648850 | 0.87 | BTN3A1 (0.41) | BTN3A1NOS2NOS3NOS1PRTN3 | |
| SCHEMBL8648854 | 0.85 | BTN3A1 (0.40) | BTN3A1TAS1R3TAS1R1POLB | |
| SCHEMBL8414853 | 0.72 | NOS3 (0.44) | NOS2NOS3NOS1GRNSORT1 | |
| Hydrochloric Acid SCHEMBL7402748 | 0.72 | NOS3 (0.42) | NOS2NOS3NOS1GRNSORT1 | |
| SCHEMBL9617379 | 0.71 | KMT2A (0.54) | NOS2MAPT | |
| SCHEMBL8639130 | 0.67 | ANPEP (0.44) | TAS1R3TAS1R1ANPEP | |
| SCHEMBL12621365 | 0.66 | ANPEP (0.47) | BTN3A1NOS2NOS3NOS1TAS1R3 | |
| SCHEMBL19441145 | 0.66 | BTN3A1 (0.70) | BTN3A1PRTN3POLB | |
| SCHEMBL19441149 | 0.66 | BTN3A1 (0.70) | BTN3A1PRTN3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760285-A | METALLOPEPTIDASE INHIBITORS | ZAMBON GROUP S.P.A. (IT) | 1998-06-02 | — | — | US | disclosed |