Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640058 | 0.90 | CTSB (0.40) | ANPEPCTSBGPR88BIRC2MEN1 | |
| SCHEMBL8642069 | 0.89 | PTPN1 (0.41) | ANPEPCTSBBIRC2MEN1KMT2A | |
| SCHEMBL8638508 | 0.87 | NPC1 (0.39) | ANPEPCTSBGPR88TAS1R3TAS1R1 | |
| SCHEMBL8642399 | 0.87 | NPC1 (0.39) | ANPEPCTSBGPR88TAS1R3TAS1R1 | |
| SCHEMBL8639883 | 0.87 | LTA4H (0.45) | CTSBMEN1KMT2A | |
| SCHEMBL8639127 | 0.87 | BIRC2 (0.41) | ANPEPCTSBGPR88BIRC2MEN1 | |
| SCHEMBL8638354 | 0.87 | LTA4H (0.45) | CTSBMEN1KMT2A | |
| SCHEMBL8640412 | 0.86 | REN (0.46) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL8645046 | 0.85 | MMP9 (0.43) | ANPEPCTSBBIRC2 | |
| SCHEMBL7404137 | 0.84 | GPR88 (0.46) | ANPEPCTSBGPR88MEN1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |