Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642917 | 0.83 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2GAAHTTMEN1 | |
| SCHEMBL8369610 | 0.82 | HTR2A (0.45) | HTR2ASLC6A4KCNH2RAB9AGAA | |
| SCHEMBL8780068 | 0.82 | HTR2A (0.45) | HTR2ASLC6A4KCNH2RAB9AGAA | |
| SCHEMBL8369608 | 0.82 | HTR2A (0.45) | HTR2ASLC6A4KCNH2RAB9AGAA | |
| SCHEMBL8769371 | 0.82 | CTNNB1 (0.57) | LMNARAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL10825614 | 0.82 | HTR2A (0.51) | HTR2ASLC6A4KCNH2LMNASMN1; SMN2 | |
| SCHEMBL6437841 | 0.81 | HTT (0.54) | HTR2ASLC6A4GAAHTTKDM4E | |
| SCHEMBL10897162 | 0.80 | ALDH1A1 (0.51) | HTR2ASLC6A4LMNASMN1; SMN2HTT | |
| SCHEMBL5405611 | 0.72 | ALDH1A1 (0.51) | SLC6A4SMN1; SMN2GAAHTTKDM4E | |
| SCHEMBL8370606 | 0.72 | HTR2A (0.40) | HTR2ASLC6A4KCNH2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770614-A | EXCELLENT ACTIVITY OF CONTROLLING PSEUDOCERCOSPORELLA HERPOTRICHOIDES | SHIONOGI & CO., LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0760363-A1 | 2-(SUBSTITUTED PHENYL)-2-ALKOXYIMINO-N-ALKYLACETAMIDE COMPOUND AND BACTERICIDE CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |