SCHEMBL8769371

SCHEMBL8769371

CNC(=O)C(=O)c1ccccc1Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.57
RAB9A P51151 1/20 0.52
L3MBTL1 Q9Y468 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
NPSR1 Q6W5P4 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 3/20 0.47
TSHR P16473 2/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
HTT P42858 2/20 0.46
MAPK8 P45983 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8642917 0.84 SMN1; SMN2 (0.48) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL6846935 0.83 RAB9A (0.63) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL8645281 0.82 HTR2A (0.51) CTNNB1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL2154374 0.81 CTNNB1 (0.51) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL2154375 0.81 CTNNB1 (0.51) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL6935927 0.81 CTNNB1 (0.59) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL11589739 0.81 CTNNB1 (0.62) CTNNB1RAB9AL3MBTL1MEN1KMT2A
SCHEMBL4782537 0.80 CTNNB1 (0.67) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL912965 0.79 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A
Metominostrobin SCHEMBL18652 0.79 RAB9A (0.49) CTNNB1RAB9AL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1051760-C (E) Process for producing (E) -alkoxyimino or hydroxyimino-acetamide compound SHIONOGI PHARMACEUTICAL K K (JP) 2000-04-26 CN disclosed
CN-1223248-A Process for producing (E)-alkoxyimino or hydroxyimino-acetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1999-07-21 CN disclosed
US-5693859-A REACTING ORTHO-SUBSTITUTED PHENYL ALPHA-KETO ACID HALIDE WITH AN AMINE YIELDS SUBSTITUTED PHENYL ALPHA-KETAMIDE SHIONOGI & CO., LTD. (JP) 1997-12-02 US disclosed
EP-0547825-B1 Process for producing alpha-ketoamide derivative SHIONOGI & CO (JP) 1997-09-03 EP disclosed
EP-0596692-B1 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1997-06-04 EP disclosed
US-5627284-A Process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO., LTD. (JP) 1997-05-06 US disclosed
EP-0741125-A1 Benzyl compounds and process for producing same SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-11-06 EP disclosed
EP-0398692-B1 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI & CO (JP) 1996-08-21 EP disclosed
US-5548078-A FOR AGRICULTURE SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-08-20 US disclosed
EP-0535928-B1 Process for producing intermediates for use in production of alkoxyiminoacetamides SHIONOGI & CO (JP) 1996-05-01 EP disclosed
US-5387714-A Alpha-keto acid halide intermediate SHIONOGI & CO., LTD. (JP) 1995-02-07 US disclosed
EP-0629609-A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-12-21 EP disclosed
US-5371222-A Intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5371223-A Controlling phytopathogens SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
EP-0596692-A2 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-11 EP disclosed
US-5258551-A Amidation of benzoyl halide derivative with organic isocyanide; fungicide intermediates SHIONOGI & CO., LTD. (JP) 1993-11-02 US disclosed
EP-0547825-A2 Process for producing alpha-ketoamide derivative SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-06-23 EP disclosed
EP-0535928-A2 Process for producing intermediates for use in production of alkoxyiminoacetamides SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-04-07 EP disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed
EP-0398692-A2 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-11-22 EP disclosed