Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PER2 | O15055 | 3/20 | 0.44 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.44 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8646719 | 0.98 | TDP1 (0.48) | TDP1ATMUSP2PER2CRY1 | |
| SCHEMBL8646533 | 0.82 | TDP1 (0.53) | TDP1USP2SMN1; SMN2TSHRMDM2 | |
| Fumaric Acid SCHEMBL8649180 | 0.76 | TDP1 (0.49) | TDP1USP2SMN1; SMN2TSHRMDM2 | |
| Fumaric Acid SCHEMBL8649177 | 0.76 | TDP1 (0.49) | TDP1USP2SMN1; SMN2TSHRMDM2 | |
| SCHEMBL8283006 | 0.74 | TDP1 (0.62) | TDP1ATMPER2CRY1CRY2 | |
| SCHEMBL8644469 | 0.74 | TDP1 (0.50) | TDP1ATMSMN1; SMN2TSHRMDM2 | |
| Hydrochloric Acid SCHEMBL8648976 | 0.73 | TDP1 (0.49) | TDP1ATMSMN1; SMN2TSHRMDM2 | |
| SCHEMBL8285114 | 0.73 | USP2 (0.56) | ATMUSP2SMN1; SMN2TSHRKMT2A | |
| SCHEMBL8644541 | 0.72 | ACHE (0.46) | TDP1SMN1; SMN2TSHRMDM2KMT2A | |
| Hydrochloric Acid SCHEMBL8646984 | 0.71 | ACHE (0.46) | TDP1SMN1; SMN2TSHRMDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |