Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.37 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8648976 | 0.99 | TDP1 (0.49) | TDP1KMT2ACTDSP1MDM2TSHR | |
| SCHEMBL8644541 | 0.80 | ACHE (0.46) | TDP1KMT2ACTDSP1MDM2TSHR | |
| Hydrochloric Acid SCHEMBL8646984 | 0.80 | ACHE (0.46) | TDP1KMT2ACTDSP1MDM2TSHR | |
| SCHEMBL8646533 | 0.77 | TDP1 (0.53) | TDP1KMT2ACTDSP1MDM2TSHR | |
| SCHEMBL8645313 | 0.74 | TDP1 (0.50) | TDP1KMT2ACTDSP1MDM2TSHR | |
| Fumaric Acid SCHEMBL8649180 | 0.73 | TDP1 (0.49) | TDP1KMT2ACTDSP1MDM2TSHR | |
| Fumaric Acid SCHEMBL8649177 | 0.73 | TDP1 (0.49) | TDP1KMT2ACTDSP1MDM2TSHR | |
| SCHEMBL8645472 | 0.73 | DRD2 (0.42) | TDP1KMT2ATSHRSMN1; SMN2ACHE | |
| Ethylene SCHEMBL8646719 | 0.72 | TDP1 (0.48) | TDP1KMT2ACTDSP1MDM2TSHR | |
| SCHEMBL8648315 | 0.72 | DRD2 (0.56) | TDP1KMT2ACTDSP1MDM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |