Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | DRD5 | P21918 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8649177 | 0.92 | TDP1 (0.49) | TDP1SMN1; SMN2TSHRKMT2AMDM2 | |
| Fumaric Acid SCHEMBL8649180 | 0.92 | TDP1 (0.49) | TDP1SMN1; SMN2TSHRKMT2AMDM2 | |
| SCHEMBL7139938 | 0.85 | DRD2 (0.64) | TDP1HTR1ADRD2HTR6DRD4 | |
| SCHEMBL8644165 | 0.83 | TDP1 (0.68) | TDP1KMT2AMDM2CTDSP1MEN1 | |
| SCHEMBL8645313 | 0.82 | TDP1 (0.50) | TDP1SMN1; SMN2TSHRKMT2AMDM2 | |
| Hydrochloric Acid SCHEMBL8643749 | 0.82 | TDP1 (0.67) | TDP1KMT2AMDM2CTDSP1MEN1 | |
| SCHEMBL6991546 | 0.82 | DRD2 (0.54) | TDP1HTR1ADRD2HTR6DRD4 | |
| SCHEMBL8786790 | 0.81 | HTR7 (0.56) | TDP1KMT2AMDM2CTDSP1HTR1A | |
| Hydrochloric Acid SCHEMBL8787804 | 0.81 | HTR7 (0.55) | TDP1KMT2AMDM2CTDSP1HTR1A | |
| SCHEMBL8648315 | 0.80 | DRD2 (0.56) | TDP1KMT2AMDM2CTDSP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |