Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611715 | 0.90 | HSP90AB1 (0.58) | ABCB1 | |
| SCHEMBL8615117 | 0.90 | MAPT (0.66) | ABCB1 | |
| SCHEMBL8613687 | 0.86 | HSP90AB1 (0.55) | ABCB1 | |
| SCHEMBL8614094 | 0.83 | MEN1 (0.69) | ABCB1 | |
| SCHEMBL8610308 | 0.83 | MEN1 (0.72) | ABCB1 | |
| SCHEMBL11194101 | 0.83 | ABCB1 (0.66) | ABCB1 | |
| SCHEMBL11818605 | 0.82 | HSP90AB1 (0.57) | ABCB1 | |
| SCHEMBL8609331 | 0.82 | MAPT (0.66) | ABCB1 | |
| Hydrochloric Acid SCHEMBL11816206 | 0.81 | HSP90AB1 (0.56) | ABCB1 | |
| SCHEMBL8637503 | 0.80 | ABCB1 (0.60) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833639-A1 | PHENOXY PIPERAZINE DERIVATIVES FOR TREATING DISORDERS OF THE DOPAMINE SYSTEM | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041630-A1 | PHENOXY PIPERAZINE DERIVATIVES FOR TREATING DISORDERS OF THE DOPAMINE SYSTEM | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-27 | — | — | WO | disclosed |