Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL923385 | 0.78 | LTA4H (0.41) | SMN1; SMN2HPGD | |
| SCHEMBL13665387 | 0.75 | ALOX15 (0.58) | HSD17B10ALOX15GAAPKMCYP1A2 | |
| SCHEMBL8642777 | 0.75 | PGR (0.56) | HSD17B10CYP1A2MAPK1MAPTRAB9A | |
| SCHEMBL8641288 | 0.73 | CYP1A2 (0.43) | HSD17B10ALOX15GAAPKMCYP1A2 | |
| Diphenylether SCHEMBL27428436 | 0.72 | NAPRT (0.76) | HSD17B10GAAMAPTALDH1A1EPHX1 | |
| SCHEMBL13200891 | 0.71 | CYP1A2 (1.00) | HSD17B10ALOX15GAAPKMCYP1A2 | |
| SCHEMBL8641407 | 0.71 | PGR (0.43) | HSD17B10CYP1A2MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL171438 | 0.70 | HPGD (0.71) | HSD17B10GAAMAPTALDH1A1EPHX1 | |
| SCHEMBL6489226 | 0.70 | MEN1 (0.46) | PKMALDH1A1RAB9APOLBHPGD | |
| SCHEMBL8645376 | 0.70 | PGR (0.55) | HSD17B10PKMALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783597-A | ANTIINFLAMMATORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |