Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646567 | 0.79 | BRD4 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL8649630 | 0.71 | ADORA2A (0.51) | VNN1ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL8648443 | 0.70 | ADORA2B (0.67) | — | |
| SCHEMBL7011613 | 0.65 | MAPK1 (0.43) | ACP1VNN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28724263 | 0.64 | CYP3A4 (0.57) | ALDH1A1POLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL7012720 | 0.63 | VNN1 (0.41) | ACP1VNN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7016174 | 0.63 | VNN1 (0.41) | ACP1VNN1ALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8649628 | 0.63 | VNN1 (0.41) | ACP1VNN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11616904 | 0.62 | NOX4 (0.42) | ALDH1A1POLBMAPTSMN1; SMN2DAO | |
| SCHEMBL1744667 | 0.62 | SRD5A2 (0.57) | VNN1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |