SCHEMBL8645685

SCHEMBL8645685

CCOC(=O)C(=O)OCc1ccc(OC)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
GLA P06280 1/20 0.54
KMT2A Q03164 1/20 0.54
HTT P42858 1/20 0.51
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MMP9 P14780 2/20 0.49
MMP1 P03956 1/20 0.49
IDO1 P14902 2/20 0.48
AGXT P21549 2/20 0.48
MMP2 P08253 1/20 0.48
MMP12 P39900 1/20 0.48
FFAR1 O14842 1/20 0.47
LDHA P00338 1/20 0.47
MAOB P27338 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
KYAT1 Q16773 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3758807 0.93 ALDH1A1 (0.60) ALDH1A1HTTNPC1POLBRAB9A
SCHEMBL28711475 0.87 ALDH1A1 (0.59) ALDH1A1KMT2AHTTNPC1POLB
SCHEMBL1521953 0.86 LTA4H (0.58) ALDH1A1HTTNPC1POLBRAB9A
SCHEMBL13034049 0.86 ALDH1A1 (0.54) ALDH1A1GLAKMT2AHTTNPC1
SCHEMBL6158485 0.84 ALDH1A1 (0.62) ALDH1A1KMT2AHTTNPC1POLB
SCHEMBL6285277 0.84 HPGD (0.56) ALDH1A1KMT2AHTTPOLBSMN1; SMN2
SCHEMBL8641118 0.84 NPC1 (0.56) ALDH1A1HTTNPC1POLBRAB9A
SCHEMBL28784413 0.83 ALDH1A1 (0.59) ALDH1A1GLAKMT2AHTTNPC1
SCHEMBL11109286 0.81 ALDH1A1 (0.50) ALDH1A1KMT2AHTTNPC1POLB
SCHEMBL292834 0.81 ALDH1A1 (0.60) ALDH1A1HTTNPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665960-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1998-08-19 EP disclosed
US-5578424-A EXPOSING A MIXTURE OF AN ACID PRECURSOR AND A DYE TO ACTINIC RADIATION TO DECOMPOSE PRECURSOR POLAROID CORPORATION (US) 1996-11-26 US disclosed
EP-0665961-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1996-10-02 EP disclosed
US-5534388-A SUPERACID PRECURSOR IS EXPOSED TO ACTINIC RADIATION TO GENERATE SUPERACID; COLORIMETRIC ANALYSIS POLAROID CORPORATION (US) 1996-07-09 US disclosed
US-5453345-A Imaging medium POLAROID CORPORATION (US) 1995-09-26 US disclosed
US-5445917-A Superacid precursor to catalyze thermal decomposition of secondary acid generator, such as squaric acid and oxalic acid derivatives; effecting color change in imaging process POLAROID CORPORATION (US) 1995-08-29 US disclosed
EP-0665961-A1 IMAGING MEDIUM AND PROCESS. POLAROID CORP (US) 1995-08-09 EP disclosed
EP-0665960-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1995-08-09 EP disclosed
US-5395736-A Exposing superoxide precursor to actinic radiation, generating superacid, mixing with oxalic acid diester, heating POLAROID CORPORATION (US) 1995-03-07 US disclosed
WO-1994010606-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed
WO-1994010607-A1 IMAGING MEDIUM AND PROCESS POLAROID CORPORATION (US) 1994-05-11 WO disclosed