Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758807 | 0.91 | ALDH1A1 (0.60) | POLBSMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL28142 | 0.87 | IDO1 (0.52) | POLBALDH1A1MAOAMAOBMEN1 | |
| SCHEMBL28711475 | 0.86 | ALDH1A1 (0.59) | POLBSMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL1521953 | 0.84 | LTA4H (0.58) | POLBSMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL8645685 | 0.84 | ALDH1A1 (0.54) | HPGDPOLBSMN1; SMN2ALDH1A1MAOB | |
| SCHEMBL6158485 | 0.83 | ALDH1A1 (0.62) | HPGDPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8641118 | 0.82 | NPC1 (0.56) | POLBSMN1; SMN2ALDH1A1HTT | |
| Carbamic Acid SCHEMBL30096670 | 0.81 | KMT2A (0.58) | HPGDPOLBSMN1; SMN2ALDH1A1MAOA | |
| SCHEMBL722902 | 0.80 | ALDH1A1 (0.60) | POLBSMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL11109286 | 0.80 | ALDH1A1 (0.50) | POLBSMN1; SMN2ALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933288-B2 | Pyranosyl cytosines: pharmaceutical formulations and methods | ISIS PHARMACEUTICALS, INC. | 2005-08-23 | — | — | US | disclosed |
| US-20030216575-A1 | Novel pyranosyl cytosines: pharmaceutical formulations and methods | ISIS PHARMACEUTICALS, INC. | 2003-11-20 | — | — | US | disclosed |
| WO-2003066633-A1 | NOVEL PYRANOSYL CYTOSINES: PHARMACEUTICAL FORMULATIONS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216575-A1 | Novel pyranosyl cytosines: pharmaceutical formulations and methods | RNGTT, NOP2, RNMT | HPGD 4079/4885POLB 344/4885LMNA 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.