Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 5/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648767 | 0.91 | PLA2G2A (0.66) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL8062575 | 0.85 | PTPN1 (0.60) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL10084151 | 0.84 | PLA2G2A (0.56) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL8231553 | 0.79 | PLA2G2A (0.50) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL8231851 | 0.79 | THRB (0.50) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL20556507 | 0.79 | THRB (0.60) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL10656972 | 0.79 | PTPN11 (0.50) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL1583340 | 0.77 | PLA2G2A (0.64) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL8640999 | 0.77 | PLA2G2A (0.64) | PLA2G2ATHRBTHRATP53TSHR | |
| SCHEMBL20556375 | 0.77 | THRB (0.64) | PLA2G2ATHRBTHRATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896533-A4 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK INC (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0896533-A2 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK, INC. (US) | 1999-02-17 | — | — | EP | disclosed |
| EP-0702668-B1 | DISCOTIC COMPOUNDS FOR USE IN LIQUID CRYSTAL MIXTURES | SECR DEFENCE BRIT (GB) | 1998-08-26 | — | — | EP | disclosed |
| US-5750050-A | Discotic compounds for use in liquid crystal mixtures | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE U.K. OF GT. BRITAIN AND N. IRELAND OF DEFENCE EVALUATION RESEARCH AGENCY, DRA (GB) | 1998-05-12 | — | — | US | disclosed |
| WO-1997030677-A2 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK, INC. (US) | 1997-08-28 | — | — | WO | disclosed |
| EP-0702668-A1 | DISCOTIC COMPOUNDS FOR USE IN LIQUID CRYSTAL MIXTURES | The Secretary of St. for Def. in her Britannic Maj. Governm of the Un. Kingdom of Gr. Brit. and N. Ireland (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029263-A1 | DISCOTIC COMPOUNDS FOR USE IN LIQUID CRYSTAL MIXTURES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1994-12-22 | — | — | WO | disclosed |