Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662625 | 0.92 | KMT2A (0.46) | PTPN11PLA2G2ATP53TSHRRARB | |
| SCHEMBL8231553 | 0.84 | PLA2G2A (0.50) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL27761938 | 0.83 | PTPN11 (0.49) | PTPN11PLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL9064238 | 0.81 | PTPN11 (0.59) | PTPN11PLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL10661049 | 0.81 | KMT2A (0.42) | PTPN11PLA2G2AKDM4EALDH1A1RAB9A | |
| SCHEMBL1262936 | 0.80 | PTGES (0.45) | MCL1KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29173955 | 0.80 | PLA2G2A (0.56) | PTPN11PLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL8645733 | 0.79 | PLA2G2A (0.59) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL13215464 | 0.78 | PLA2G2A (0.57) | PLA2G2ATP53TSHRPLA2G4BRARB | |
| SCHEMBL8974262 | 0.78 | PTPN11 (0.64) | PTPN11PLA2G2ATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |