Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152838 | 0.80 | MMP2 (0.45) | MMP2MMP9ACETLR2FOLH1 | |
| SCHEMBL5840486 | 0.80 | MMP2 (0.45) | MMP2MMP9ACETLR2FOLH1 | |
| SCHEMBL8664220 | 0.80 | MMP2 (0.45) | MMP2MMP9ACETLR2FOLH1 | |
| SCHEMBL6152839 | 0.76 | MMP2 (0.49) | MMP2MMP9TLR2FOLH1CA1 | |
| SCHEMBL5840489 | 0.76 | MMP2 (0.49) | MMP2MMP9TLR2FOLH1CA1 | |
| SCHEMBL17102265 | 0.75 | MMP2 (0.46) | MMP2MMP9ALDH1A1ACETLR2 | |
| SCHEMBL7757254 | 0.75 | MMP2 (0.46) | MMP2MMP9TLR2FOLH1CA1 | |
| Phthalic Acid SCHEMBL19210210 | 0.74 | GSR (0.67) | MMP2ALDH1A1 | |
| Phthalic Acid SCHEMBL19210211 | 0.74 | GSR (0.67) | MMP2ALDH1A1 | |
| SCHEMBL7226850 | 0.74 | MMP2 (0.50) | MMP2MMP9TLR2ANPEPECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861260-A1 | IMPROVED METHOD AND AGENTS FOR INHIBITING PROTEIN AGING | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018223-A1 | IMPROVED METHOD AND AGENTS FOR INHIBITING PROTEIN AGING | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1997-05-22 | — | — | WO | disclosed |