Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647266 | 0.86 | KMT2A (0.37) | ALDH1A1KDM4ELMNAKMT2ANPC1 | |
| SCHEMBL8646109 | 0.83 | GAA (0.42) | ALDH1A1KDM4ELMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8645634 | 0.82 | BRD4 (0.40) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL8645638 | 0.81 | BRD4 (0.40) | ALDH1A1LMNAMAPT | |
| SCHEMBL8645682 | 0.81 | HSD17B3 (0.39) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL8646116 | 0.80 | GAA (0.42) | ALDH1A1KDM4ELMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8645683 | 0.79 | HSD17B3 (0.37) | ALDH1A1KDM4EHPGDKMT2ANPC1 | |
| SCHEMBL8644832 | 0.76 | TUBB4A (0.37) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL8644828 | 0.76 | TUBB4A (0.38) | ALDH1A1KDM4EKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8647255 | 0.75 | TUBB4A (0.35) | ALDH1A1KDM4EKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843972-A | Heterocyclic β-adrenergic agonists | PFIZER INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0801060-A1 | Heterocyclic Beta-3 Adrenergenic Agonists | PFIZER INC. (US) | 1997-10-15 | — | — | EP | disclosed |