Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645683 | 0.95 | HSD17B3 (0.37) | HSD17B3MEN1KMT2AALDH1A1TUBB4A | |
| SCHEMBL8644828 | 0.86 | TUBB4A (0.38) | HSD17B3MEN1KMT2AALDH1A1TUBB4A | |
| SCHEMBL8644832 | 0.84 | TUBB4A (0.37) | HSD17B3MEN1KMT2AALDH1A1TUBB4A | |
| SCHEMBL8646109 | 0.84 | GAA (0.42) | HSD17B3MEN1KMT2AALDH1A1TUBB4A | |
| SCHEMBL8645858 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8645900 | 0.81 | MAPT (0.34) | NOTUMMAPTPOLBHDAC1HDAC6 | |
| SCHEMBL8646116 | 0.80 | GAA (0.42) | MEN1KMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL8647250 | 0.80 | TUBB4A (0.36) | HSD17B3KMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL8647255 | 0.78 | TUBB4A (0.35) | HSD17B3KMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL8645908 | 0.76 | MAPT (0.35) | NOTUMMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843972-A | Heterocyclic β-adrenergic agonists | PFIZER INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0801060-A1 | Heterocyclic Beta-3 Adrenergenic Agonists | PFIZER INC. (US) | 1997-10-15 | — | — | EP | disclosed |