Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716884 | 0.84 | PDK1 (0.51) | PDK1PDK2PDK3PDK4TP53 | |
| SCHEMBL432229 | 0.84 | KCNK2 (0.55) | ALDH1A1HPGDPDK1PDK2PDK3 | |
| SCHEMBL3078843 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL943096 | 0.82 | PDK1 (0.71) | ALDH1A1HPGDPOLBPDK1PDK2 | |
| SCHEMBL3591716 | 0.82 | PDK1 (0.50) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL9478517 | 0.82 | PDK1 (0.50) | PDK1PDK2PDK3PDK4TP53 | |
| SCHEMBL5365142 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| Trifluoroacetic Acid SCHEMBL3600528 | 0.80 | SIRT2 (0.57) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL159515 | 0.80 | AGTR1 (0.50) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL31128489 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HPGDPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622959-A1 | 2-AMINO-N-(4-AMINO-3,4-DIOXO-1-(2-OXOPYRROLIDIN-3-YL)BUTAN-2-YL)BENZAMIDE DERIVATIVES AS PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | Merck Sharp & Dohme LLC (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112621-A1 | 2-AMINO-N-(4-AMINO-3,4-DIOXO-1-(2-OXOPYRROLIDIN-3-YL)BUTAN-2-YL)BENZAMIDE DERIVATIVES AS PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | MERCK SHARP & DOHME LLC (US) | 2024-05-30 | — | — | WO | disclosed |
| CN-1293665-A | New compounds and their use as positive AMPA receptor modulators | NEUROSEARCH AS (DK) | 2001-05-02 | — | — | CN | disclosed |
| EP-0545491-B1 | Photographic silver halide colour materials | KODAK LTD (GB) | 1998-10-14 | — | — | EP | disclosed |
| EP-0565165-B1 | Photographic silver halide colour materials | KODAK LTD (GB) | 1998-09-02 | — | — | EP | disclosed |
| EP-0775110-A1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004242-A1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5415981-A | Sulfohydrazide developer, heteroarylacetonitrile color coupler | EASTMAN KODAK COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5284739-A | Devloper and coupler present in drops of a high-boiling solvent; water pollution control | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0565165-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-10-13 | — | — | EP | disclosed |
| EP-0545491-A1 | Photographic silver halide colour materials | KODAK LIMITED (GB) | 1993-06-09 | — | — | EP | disclosed |