Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546274 | 0.82 | LMNA (0.44) | LMNAKDM4EMAPTALDH1A1MAPK1 | |
| SCHEMBL8396067 | 0.81 | NISCH (0.38) | KDM4EMAPTALDH1A1SNCATSHR | |
| SCHEMBL8396050 | 0.80 | RECQL (0.44) | KDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL8398969 | 0.80 | MAPT (0.39) | LMNAKDM4EMAPTALDH1A1POLB | |
| SCHEMBL8400501 | 0.80 | FFAR1 (0.40) | LMNAKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL8396086 | 0.79 | TP53 (0.47) | LMNAKDM4EALDH1A1TP53NPC1 | |
| SCHEMBL8499915 | 0.79 | KDM4E (0.32) | LMNAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8399047 | 0.79 | GRM5 (0.39) | LMNAKDM4EMAPTALDH1A1TP53 | |
| SCHEMBL8846363 | 0.79 | PTGER4 (0.42) | LMNAMAPTALDH1A1MAPK1POLB | |
| SCHEMBL8395326 | 0.79 | LMNA (0.43) | LMNAKDM4EMAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770614-A | EXCELLENT ACTIVITY OF CONTROLLING PSEUDOCERCOSPORELLA HERPOTRICHOIDES | SHIONOGI & CO., LTD. (JP) | 1998-06-23 | — | — | US | disclosed |