Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396306 | 0.91 | HIF1A (0.42) | HIF1ASMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL8400501 | 0.90 | FFAR1 (0.40) | HIF1ALMNAKDM4EALDH1A1MAPT | |
| SCHEMBL8400207 | 0.87 | CYP3A4 (0.38) | GRM5HIF1ASMN1; SMN2F2LMNA | |
| SCHEMBL8397983 | 0.87 | TDP1 (0.41) | HIF1ASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL8846363 | 0.84 | PTGER4 (0.42) | LMNAALDH1A1MAPT | |
| SCHEMBL8399075 | 0.84 | KMT2A (0.42) | LMNAKDM4EALDH1A1MAOB | |
| SCHEMBL8399059 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL8399231 | 0.84 | HIF1A (0.44) | HIF1AMAOB | |
| SCHEMBL896797 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL8397935 | 0.84 | MRGPRX4 (0.41) | HIF1ASMN1; SMN2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |