Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.55 |
| ▸ | NQO2 | P16083 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643820 | 0.98 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL8638751 | 0.95 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL8643655 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL8643878 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL8643630 | 0.82 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8639949 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL8646700 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9017429 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL8641737 | 0.79 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2KDM4EALDH1A1 | |
| SCHEMBL8646238 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BNQO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| JP-8333315-A | — | — | None | — | — | JP | disclosed |
| US-5736578-A | TREATMENT OF SLEEP DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| JP-H08333315-A | ETHYLAMIDO FLUORENE AND ITS IMPROVED PRODUCTION | BRISTOL MYERS SQUIBB CO | 1996-12-17 | — | — | JP | disclosed |
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |