Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608505 | 0.69 | KMT2A (0.44) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL15200988 | 0.66 | LMNA (0.58) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11494801 | 0.66 | ALDH1A1 (0.39) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11781977 | 0.65 | ALDH1A1 (0.43) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11779254 | 0.64 | ALDH1A1 (0.43) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11775267 | 0.64 | ALDH1A1 (0.43) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11779505 | 0.62 | CASP6 (0.42) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11780419 | 0.62 | CASP6 (0.42) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11776524 | 0.62 | ALDH1A1 (0.48) | MAPTKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL14534706 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712408-A | Diaminomaleonitrile derivative compounds, polymers, and method of producing same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-27 | — | — | US | disclosed |