Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530258 | 0.88 | KMT2A (0.64) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL18095346 | 0.88 | TSHR (0.54) | HDAC6HDAC2HDAC8KMT2ATSHR | |
| SCHEMBL1899410 | 0.87 | NPSR1 (0.57) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL2828029 | 0.86 | F10 (0.57) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL19634801 | 0.85 | SLC7A5 (0.58) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL19634740 | 0.85 | LOXL2 (0.64) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4623980 | 0.85 | TSHR (0.55) | TSHRNR1H4CYP19A1MMP13MAOB | |
| SCHEMBL10131961 | 0.84 | NOS1 (0.51) | KMT2ATSHRCYP19A1MAOBALDH1A1 | |
| SCHEMBL25779414 | 0.83 | TSHR (0.47) | KMT2ATSHRNR1H4CYP19A1MMP13 | |
| SCHEMBL8647807 | 0.83 | HDAC1 (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545376-B1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5532258-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| WO-1996005187-A1 | (4-(3-AMINOMETHYLPHENYL)THIAZOL-2-YL)-GUANIDINES AS H2-RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |
| CN-1089259-A | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-13 | — | — | CN | disclosed |
| CN-1079469-A | Preparation method with thiazole derivative of antiulcer activity and Histamine Receptors antagonistic action | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-12-15 | — | — | CN | disclosed |
| EP-0545376-A1 | Guanidino thiazoles and their use as H2-receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |