Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8644566 | 0.93 | MEN1 (0.38) | MC4RMEN1KMT2AMAOBACHE | |
| Fumaric Acid SCHEMBL8644575 | 0.93 | MEN1 (0.38) | MC4RMEN1KMT2AMAOBACHE | |
| SCHEMBL8643747 | 0.77 | MTR (0.44) | MEN1KMT2A | |
| SCHEMBL8649403 | 0.76 | MTR (0.43) | MEN1KMT2ABCHEHTR1ANPC1 | |
| SCHEMBL8644064 | 0.72 | MTR (0.38) | MEN1KMT2ABCHENPC1RAB9A | |
| SCHEMBL8646569 | 0.70 | TDP1 (0.43) | MC4RKMT2AMAOBSIGMAR1ACHE | |
| Fumaric Acid SCHEMBL8643277 | 0.70 | ALDH1A1 (0.39) | MEN1KMT2AACHEMAPT | |
| SCHEMBL8644571 | 0.70 | LMNA (0.35) | MAOBACHEBCHEMAPTHTR1A | |
| Hydrochloric Acid SCHEMBL8647131 | 0.70 | TDP1 (0.43) | MC4RKMT2AMAOBSIGMAR1ACHE | |
| SCHEMBL8787526 | 0.68 | ALDH1A1 (0.42) | MC4RMEN1KMT2AACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |