Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 3/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661932 | 0.87 | MCOLN3 (0.58) | PTGES2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8645956 | 0.84 | MCL1 (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGMCL1 | |
| SCHEMBL8645738 | 0.84 | NAT1 (0.60) | PTGES2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8657936 | 0.82 | PTGES2 (0.52) | PTGES2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8648154 | 0.82 | PTGS2 (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGACLY | |
| SCHEMBL8649422 | 0.81 | PTGES2 (0.56) | PTGES2KAT6APGAM1ACLYPGR | |
| SCHEMBL8645479 | 0.77 | ACLY (0.57) | PIK3CAPGAM1ACLYCA12CA9 | |
| SCHEMBL8650268 | 0.77 | MCL1 (0.51) | PTGES2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8659718 | 0.77 | KAT6A (0.54) | KAT6APGRNPSR1 | |
| SCHEMBL8658030 | 0.76 | HPGD (0.51) | PTGES2PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843999-A | 2-phenylazulene derivatives and a manufacturing method of these compounds | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |