Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 14/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663418 | 0.87 | STAT3 (0.59) | PTGS2PTGS1STAT3 | |
| SCHEMBL8650268 | 0.85 | MCL1 (0.51) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8645738 | 0.85 | NAT1 (0.60) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8657396 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1ACLYSTAT3 | |
| SCHEMBL8646611 | 0.82 | ACLY (0.60) | PTGS2PTGS1ACLY | |
| SCHEMBL8646709 | 0.82 | PTGES2 (0.48) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8660105 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1ACLY | |
| SCHEMBL8645956 | 0.77 | MCL1 (0.62) | ACLYPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8658333 | 0.77 | STAT3 (0.59) | ACLYSTAT3 | |
| SCHEMBL8659417 | 0.77 | HPGD (0.48) | PTGS2PTGS1ACLYSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843999-A | 2-phenylazulene derivatives and a manufacturing method of these compounds | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |