Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 10/20 | 0.63 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21754423 | 0.90 | PTGFR (0.78) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL25177987 | 0.81 | PTGFR (0.75) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL25177988 | 0.81 | PTGFR (0.75) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL18532333 | 0.81 | PTGFR (0.78) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL13137214 | 0.81 | ABCB11 (0.81) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL8604245 | 0.79 | SLCO2A1 (0.79) | PTGFRPTGER3PTGER1SLCO2A1ABCB11 | |
| SCHEMBL10024575 | 0.79 | PTGFR (0.63) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| SCHEMBL10057560 | 0.79 | PTGFR (0.63) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| Tiaprost SCHEMBL867741 | 0.78 | PTGFR (0.78) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 | |
| Tiaprost SCHEMBL14511288 | 0.78 | PTGFR (0.78) | PTGFRPTGER3TBXA2RPTGER1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834498-A | OCULAR HYPOTENSIVE AGENTS | ALLERGAN (US) | 1998-11-10 | — | — | US | disclosed |