SCHEMBL8647680

SCHEMBL8647680

CON(C)C(=O)[C@H](COC(C)(C)C)N(C(=O)O)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19458517 0.83 FAAH (0.32) FAAH
SCHEMBL1642220 0.83 FAAH (0.32) FAAH
SCHEMBL29941035 0.83 FAAH (0.32) FAAH
SCHEMBL12475634 0.83 FAAH (0.32) FAAH
SCHEMBL19458516 0.83 FAAH (0.32) FAAH
SCHEMBL14910212 0.83 FAAH (0.32) FAAH
SCHEMBL17373217 0.78
SCHEMBL6408059 0.78 CA2 (0.36) MAPK1
SCHEMBL1126593 0.74 FAAH (0.44) MAPK1FAAH
SCHEMBL21526204 0.74 FAAH (0.44) MAPK1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726185-A BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION HOFFMANN-LA ROCHE INC. (US) 1998-03-10 US disclosed