SCHEMBL8647682

SCHEMBL8647682

CON(C)C(=O)C(NC(=O)O)[C@H](OC(C)(C)C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.32
BTK Q06187 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383198 0.83 JAK3 (0.32) JAK3BTK
SCHEMBL19746826 0.79 FAAH (0.35)
SCHEMBL4480182 0.79 FAAH (0.35)
SCHEMBL8644854 0.78 JAK3 (0.32) JAK3BTK
SCHEMBL15736879 0.74 PDF (0.37) JAK3BTK
SCHEMBL8646564 0.71 FAAH (0.37) JAK3BTK
SCHEMBL8647573 0.70 NPSR1 (0.45)
SCHEMBL4476337 0.69 CTSK (0.49) JAK3BTK
SCHEMBL4476340 0.69 CTSK (0.49) JAK3BTK
SCHEMBL1655475 0.69 CTSK (0.49) JAK3BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726185-A BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION HOFFMANN-LA ROCHE INC. (US) 1998-03-10 US disclosed