Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647900 | 0.76 | PGR (0.55) | PGR | |
| SCHEMBL16268679 | 0.70 | PGR (0.41) | PGR | |
| SCHEMBL16268678 | 0.70 | PGR (0.41) | PGR | |
| SCHEMBL19599271 | 0.70 | NR3C1 (0.33) | PGR | |
| SCHEMBL1128004 | 0.69 | ALDH1A1 (0.47) | PGRKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL4773759 | 0.68 | NPC1 (0.37) | PGRACHEHTTNPC1CASP3 | |
| SCHEMBL7147326 | 0.67 | PGR (0.35) | PGRACHEKDM4EALDH1A1NPC1 | |
| SCHEMBL28957609 | 0.67 | PGR (0.37) | PGRKDM4EALDH1A1MAPTHTT | |
| SCHEMBL13039618 | 0.66 | NPC1 (0.41) | PGRACHEHTTNPC1CASP3 | |
| SCHEMBL28957621 | 0.66 | PGR (0.39) | PGRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808139-A | CONTROLLING COMPLEXING WITH CYMOPOLY COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0637296-A4 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS. | LIGAND PHARM INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0637296-A1 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1994024080-A1 | PROGESTERONE RECEPTOR AGONIST AND ANTAGONISTS | LIGAND PHARMACEUTICALS INC. (US) | 1994-10-27 | — | — | WO | disclosed |
| WO-1993021145-A1 | NON-STEROID PROGESTERONE RECEPTOR AGONIST AND ANTAGONIST COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | disclosed |