Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762267 | 0.92 | CES2 (0.52) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL6682499 | 0.91 | CES2 (0.55) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL2761265 | 0.91 | CES2 (0.55) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL14856629 | 0.91 | CES2 (0.55) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL719395 | 0.91 | CES2 (0.55) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL8823207 | 0.91 | CES2 (0.55) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL12227837 | 0.86 | CA1 (0.65) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL41021 | 0.86 | CA1 (0.65) | MAPTALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL10033153 | 0.80 | ESR2 (0.64) | MAPTALDH1A1ALOX15LMNAAPEX1 | |
| SCHEMBL13211691 | 0.79 | ESR2 (0.56) | MAPTALDH1A1ALOX15LMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670310-B1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0670310-A1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-09-06 | — | — | EP | disclosed |