Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856629 | 1.00 | CES2 (0.55) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL719395 | 1.00 | CES2 (0.55) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL2761265 | 1.00 | CES2 (0.55) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL8823207 | 1.00 | CES2 (0.55) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL10762267 | 0.98 | CES2 (0.52) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL8648263 | 0.91 | MAPT (0.55) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL7953 | 0.87 | CES2 (0.69) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL9102 | 0.87 | CES2 (0.69) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL28067932 | 0.87 | CA4 (0.59) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL10112758 | 0.87 | CA4 (0.59) | CES2CES1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474432-A1 | IMMUNOSTIMULATORY, COVALENTLY LIPIDATED OLIGONUCLEOTIDES | Biomira Inc. (CA) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066649-A1 | IMMUNOSTIMULATORY, COVALENTLY LIPIDATED OLIGONUCLEOTIDES | BIOMIRA INC. (CA) | 2003-08-14 | — | — | WO | disclosed |
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0191659-A1 | Derivatives of adenosine nucleosides, their preparation and their biological use | INSTITUT PASTEUR (FR) | 1986-08-20 | — | — | EP | disclosed |
| EP-0124561-A1 | PROCESS FOR PRODUCING OLIGONUCLEOSIDE PHOSPHONATES. | KOSTER HUBERT | 1984-11-14 | — | — | EP | disclosed |
| WO-1984001778-A1 | PROCESS FOR PRODUCING OLIGONUCLEOSIDE PHOSPHONATES | KOESTER HUBERT (DE) | 1984-05-10 | — | — | WO | disclosed |