SCHEMBL10033153

SCHEMBL10033153

COc1ccc(C(c2ccc(O)cc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.64
LTA4H P09960 1/20 0.64
APP P05067 2/20 0.57
CALM1 P0DP23 1/20 0.53
GAA P10253 1/20 0.53
PKM P14618 1/20 0.53
LMNA P02545 2/20 0.52
TYR P14679 1/20 0.52
MAPT P10636 1/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
S100B P04271 1/20 0.47
MAPK1 P28482 2/20 0.47
ABL1 P00519 1/20 0.47
ABCB1 P08183 1/20 0.47
BCR P11274 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23626098 0.92 ESR2 (0.55) ESR2LTA4HAPPCALM1GAA
SCHEMBL12227837 0.88 CA1 (0.65) LTA4HGAALMNAMAPTCA12
Mequinol SCHEMBL21009 0.85
1,4-Dimethoxybenzene SCHEMBL8351066 0.85 ESR2 (0.84) ESR2LTA4HAPPCALM1GAA
Mequinol SCHEMBL1535640 0.85 ESR2 (0.84) ESR2LTA4HAPPCALM1GAA
Mequinol SCHEMBL166535 0.85 ESR2 (0.84) ESR2LTA4HAPPCALM1GAA
SCHEMBL822911 0.84 ESR2 (0.70) ESR2LTA4HAPPCALM1GAA
SCHEMBL4656148 0.84 ESR2 (0.61) ESR2LTA4HAPPCALM1GAA
SCHEMBL9171254 0.84 ESR2 (0.61) ESR2LTA4HAPPCALM1GAA
Mequinol SCHEMBL16338066 0.83 ESR2 (0.80) ESR2LTA4HAPPCALM1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947393-B2 Coating agent NIPPON SODA CO., LTD. (JP) 2021-03-16 US disclosed
EP-2949716-B1 COATING AGENT NIPPON SODA CO (JP) 2020-04-29 EP disclosed
US-20150353738-A1 COATING AGENT NIPPON SODA CO., LTD. (JP) 2015-12-10 US disclosed
EP-2949716-A1 COATING AGENT Nippon Soda Co., Ltd. (JP) 2015-12-02 EP disclosed
WO-2012032211-A1 DENDRITIC STRUCTURES BASED ON TETRAARYLMETHANE UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353738-A1 COATING AGENT ITGA1, ITGA2, L1CAM ESR2 151/4885LTA4H 2771/4885APP 1805/4885
US-10947393-B2 Coating agent ITGA1, ITGA2, L1CAM ESR2 151/4885LTA4H 2771/4885APP 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.