Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 10/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8645889 | 0.99 | TDP1 (0.52) | TDP1BCHECARM1PRMT6PRMT8 | |
| SCHEMBL8648721 | 0.85 | TDP1 (0.49) | TDP1CARM1PRMT6MDM2KMT2A | |
| Hydrochloric Acid SCHEMBL8645866 | 0.84 | TDP1 (0.48) | TDP1CARM1PRMT6MDM2KMT2A | |
| SCHEMBL8649704 | 0.84 | TDP1 (0.56) | TDP1CARM1PRMT6PRMT8TMEM97 | |
| Ethylene SCHEMBL8643250 | 0.84 | TDP1 (0.47) | TDP1CARM1PRMT6MDM2KMT2A | |
| Hydrochloric Acid SCHEMBL8787330 | 0.83 | TDP1 (0.55) | TDP1TMEM97SIGMAR1MDM2KMT2A | |
| SCHEMBL8644165 | 0.82 | TDP1 (0.68) | TDP1MDM2KMT2ACTDSP1 | |
| Hydrochloric Acid SCHEMBL8643749 | 0.81 | TDP1 (0.67) | TDP1MDM2KMT2ACTDSP1 | |
| SCHEMBL8644528 | 0.78 | TDP1 (0.58) | TDP1CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL7139938 | 0.77 | DRD2 (0.64) | TDP1DRD2DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |