Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8643749 | 0.99 | TDP1 (0.67) | TDP1KMT2AMDM2CTDSP1MAPT | |
| SCHEMBL7139938 | 0.86 | DRD2 (0.64) | TDP1 | |
| SCHEMBL8649704 | 0.84 | TDP1 (0.56) | TDP1KMT2AMDM2CTDSP1 | |
| Hydrochloric Acid SCHEMBL8787330 | 0.83 | TDP1 (0.55) | TDP1KMT2AMDM2CTDSP1 | |
| SCHEMBL8646533 | 0.83 | TDP1 (0.53) | TDP1KMT2AMDM2CTDSP1MEN1 | |
| SCHEMBL8648315 | 0.83 | DRD2 (0.56) | TDP1KMT2AMDM2CTDSP1MEN1 | |
| Hydrochloric Acid SCHEMBL8645737 | 0.82 | DRD2 (0.55) | TDP1KMT2AMDM2CTDSP1MEN1 | |
| SCHEMBL8648331 | 0.82 | TDP1 (0.53) | TDP1KMT2AMDM2CTDSP1 | |
| Hydrochloric Acid SCHEMBL8645889 | 0.81 | TDP1 (0.52) | TDP1KMT2AMDM2CTDSP1 | |
| SCHEMBL6991546 | 0.80 | DRD2 (0.54) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |