Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8787330 | 0.99 | TDP1 (0.55) | TDP1CCR3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL8644528 | 0.93 | TDP1 (0.58) | TDP1CCR3SIGMAR1MDM2KMT2A | |
| Hydrochloric Acid SCHEMBL8649115 | 0.92 | TDP1 (0.57) | TDP1CCR3SIGMAR1MDM2KMT2A | |
| SCHEMBL8788275 | 0.89 | OPRM1 (0.49) | TDP1SLC6A2SLC6A4KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL8786910 | 0.88 | OPRM1 (0.48) | TDP1SLC6A2SLC6A4KMT2ADRD2 | |
| SCHEMBL8648331 | 0.84 | TDP1 (0.53) | TDP1SIGMAR1MDM2KMT2ACTDSP1 | |
| SCHEMBL8644165 | 0.84 | TDP1 (0.68) | TDP1MDM2KMT2ACTDSP1 | |
| Hydrochloric Acid SCHEMBL8645889 | 0.83 | TDP1 (0.52) | TDP1SIGMAR1MDM2KMT2ACTDSP1 | |
| Hydrochloric Acid SCHEMBL8643749 | 0.83 | TDP1 (0.67) | TDP1MDM2KMT2ACTDSP1 | |
| SCHEMBL8648721 | 0.82 | TDP1 (0.49) | TDP1MDM2KMT2ACTDSP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |