Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 5/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648445 | 1.00 | DGKA (0.48) | DGKATSHRLMNANAAAPAM | |
| SCHEMBL1036873 | 0.83 | ALDH1A1 (0.62) | DGKATSHRLMNAPAMMAPT | |
| SCHEMBL28515768 | 0.82 | CES2 (0.44) | DGKATSHRALDH1A1CES2CES1 | |
| SCHEMBL4645612 | 0.81 | CES2 (0.44) | DGKATSHRALDH1A1CES2CES1 | |
| SCHEMBL9019586 | 0.81 | CES2 (0.44) | DGKATSHRALDH1A1CES2CES1 | |
| SCHEMBL50250 | 0.81 | DGKA (0.64) | DGKATSHRLMNAPAMMAPT | |
| SCHEMBL9019580 | 0.81 | CES2 (0.44) | DGKATSHRALDH1A1CES2CES1 | |
| SCHEMBL7156970 | 0.81 | DGKA (0.64) | DGKATSHRLMNAPAMMAPT | |
| SCHEMBL15528070 | 0.81 | DGKA (0.64) | DGKATSHRLMNAPAMMAPT | |
| SCHEMBL4645615 | 0.81 | CES2 (0.44) | DGKATSHRALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756553-A | Medical material and process for producing the same | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-05-26 | — | — | US | disclosed |