SCHEMBL8648652

SCHEMBL8648652

Sc1ccn2ncnc2n1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.45
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAP4K4 O95819 3/20 0.33
GAA P10253 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPK1 P28482 1/20 0.31
KCNH2 Q12809 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9933093 0.75 PDE10A (0.45) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL362643 0.75 PDE10A (0.45) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL5188673 0.75 PDE10A (0.45) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL9372254 0.75 KDM4E (0.45) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL9933877 0.71 PDE10A (0.41) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL22755250 0.71 PDE10A (0.41) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL12603986 0.71 ALDH1A1 (0.42) PDE10AKDM4EALDH1A1MAP4K4GAA
SCHEMBL22109267 0.65 KDM4E (0.38) PDE10AKDM4EALDH1A1MAPK1KCNH2
SCHEMBL72796 0.62
SCHEMBL9634611 0.61 PDE10A (0.95) PDE10AKDM4EALDH1A1MAP4K4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439041-B1 Direct positive photographic material FUJI PHOTO FILM CO LTD (JP) 1998-09-02 EP disclosed
EP-0399460-B1 Silver halide photograpic material FUJI PHOTO FILM CO LTD (JP) 1996-10-23 EP disclosed
EP-0393477-B1 Direct positive photosensitive material FUJI PHOTO FILM CO LTD (JP) 1996-07-03 EP disclosed
EP-0355818-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1995-05-10 EP disclosed
EP-0322702-B1 Direct positive photographic materials FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
US-5185241-A Non-fogged internal latent image-type silver halide grains that contain at least one metal FUJI PHOTO FILM CO., LTD. (JP) 1993-02-09 US disclosed
EP-0318987-B1 DIRECT POSITIVE PHOTOGRAPHIC LIGHTSENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-02-03 EP disclosed
US-H1119-H Improved time-dependent storage stability FUJI PHOTO FILM CO., LTD. (JP) 1992-12-01 US disclosed
EP-0276842-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-07-29 EP disclosed
US-5104784-A Containing organic thiosulfurous and inorganic sulfurous acid derivatives; storage stable sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1992-04-14 US disclosed
EP-0355818-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-02-28 EP disclosed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
US-4859579-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed
EP-0322702-A2 Direct positive photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0318987-A1 Direct positive photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-07 EP disclosed
EP-0315890-A1 Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1989-05-17 EP disclosed
EP-0303301-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-02-15 EP disclosed
EP-0276842-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-08-03 EP disclosed
EP-0267482-A2 Direct positive color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-05-18 EP disclosed
US-4358530-A SUPPORTED NONSILVER PHOTOGRAPHIC LAYER HAVING A SILVER HALIDE EMULSION COATING CONTAINING A PHENYL HYDRAZIDE FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 US disclosed