Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648985 | 1.00 | ALDH1A1 (0.63) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL6500171 | 0.92 | RELA (0.59) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL3973218 | 0.92 | RELA (0.59) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL11351372 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL6964436 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL6964447 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL9276383 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL9276381 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4RECQLRELAPTGS1 | |
| SCHEMBL10746614 | 0.78 | CNR2 (0.55) | ALDH1A1CYP3A4RELAPTGS1HDAC1 | |
| SCHEMBL10746611 | 0.78 | CNR2 (0.55) | ALDH1A1CYP3A4RELAPTGS1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399676-A | DNA sequence identification | GILEAD SCIENCES (US) | 1995-03-21 | — | — | US | claimed |
| US-5721218-A | Oligonucleotides with inverted polarity | GILEAD SCIENCES, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5527899-A | STABILIZATION THE SINGLE-STRAND OLIGONUCLEOTIDE TO EXONUCLEASE DEGRADATION | GILEAD SCIENCES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5399676-A | DNA sequence identification | GILEAD SCIENCES (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0539371-A1 | TRIPLE HELIX FORMATION IN OLIGONUCLEOTIDE THERAPY | GILEAD SCIENCES, INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991006626-A2 | TRIPLE HELIX FORMATION IN OLIGONUCLEOTIDE THERAPY | GILEAD SCIENCES, INC. (US) | 1991-05-16 | — | — | WO | disclosed |