Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646303 | 0.97 | MEN1 (0.36) | LMNAMEN1HTTKMT2ACXCR4 | |
| SCHEMBL8645303 | 0.95 | CXCR4 (0.38) | LMNAMEN1HTTKMT2ACXCR4 | |
| SCHEMBL8650254 | 0.92 | MEN1 (0.35) | LMNAMEN1HTTKMT2ACXCR4 | |
| SCHEMBL8648971 | 0.90 | TSHR (0.36) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL8650000 | 0.87 | GAA (0.35) | LMNAHTTKMT2ACXCR4ALDH1A1 | |
| SCHEMBL8648783 | 0.87 | DHFR (0.39) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL8649688 | 0.87 | TSHR (0.38) | LMNAMEN1HTTKMT2ATSHR | |
| SCHEMBL8651827 | 0.84 | GAA (0.33) | MEN1KMT2AMMP2MMP9MMP1 | |
| SCHEMBL8649659 | 0.83 | DHFR (0.40) | MEN1KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL8323058 | 0.82 | LMNA (0.40) | LMNAMEN1HTTKMT2ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |