Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648971 | 0.97 | TSHR (0.36) | TSHRDHFRGRM2HSD11B1DDB1 | |
| SCHEMBL8649659 | 0.97 | DHFR (0.40) | TSHRDHFRGRM2HSD11B1DDB1 | |
| SCHEMBL8648783 | 0.94 | DHFR (0.39) | TSHRDHFRGRM2HSD11B1DDB1 | |
| SCHEMBL8649675 | 0.91 | GAA (0.35) | TSHRDHFRGRM2HSD11B1DDB1 | |
| SCHEMBL8649669 | 0.88 | DHFR (0.35) | TSHRDHFRGRM2HSD11B1DDB1 | |
| SCHEMBL8649073 | 0.87 | LMNA (0.39) | TSHRALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL8645303 | 0.86 | CXCR4 (0.38) | TSHRALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL8646303 | 0.83 | MEN1 (0.36) | TSHRDHFRALDH1A1LMNAMEN1 | |
| SCHEMBL8650254 | 0.83 | MEN1 (0.35) | DHFRHSD11B1ALDH1A1HPGDLMNA | |
| SCHEMBL8649233 | 0.80 | TP53 (0.39) | TSHRDHFRHSD11B1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |