Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 6/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643863 | 1.00 | ELANE (0.44) | ELANEHSD11B1MMP13MMP2MMP1 | |
| SCHEMBL8643779 | 0.95 | ELANE (0.48) | ELANEHSD11B1MMP2ALDH1A1KDM1A | |
| SCHEMBL8648382 | 0.90 | CYP3A4 (0.39) | ELANEHSD11B1MMP13MMP2MMP1 | |
| SCHEMBL8646164 | 0.90 | CYP3A4 (0.39) | ELANEHSD11B1MMP13MMP2MMP1 | |
| SCHEMBL8648000 | 0.86 | ELANE (0.38) | ELANEHSD11B1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8651584 | 0.84 | PSEN1 (0.47) | CYP2C19ALDH1A1CYP2C9HPGDCA2 | |
| SCHEMBL8651818 | 0.83 | HSD11B1 (0.38) | HSD11B1MMP13MMP2MMP1CYP3A4 | |
| SCHEMBL8646731 | 0.83 | HSD11B1 (0.38) | HSD11B1MMP13MMP2MMP1CYP3A4 | |
| SCHEMBL8323469 | 0.83 | ELANE (0.50) | ELANEHSD11B1MMP13MMP2MMP1 | |
| SCHEMBL8969045 | 0.81 | ELANE (0.51) | ELANEHSD11B1MMP13KDM1ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |