Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649361 | 1.00 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL27520778 | 0.85 | RAB9A (0.42) | KMT2AMEN1ALDH1A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL8667384 | 0.84 | RAB9A (0.41) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL8645503 | 0.82 | ALDH1A1 (0.74) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8645501 | 0.82 | ALDH1A1 (0.74) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8650792 | 0.82 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL8650796 | 0.82 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL8644315 | 0.80 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL8644310 | 0.80 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL8643121 | 0.80 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861831-A1 | HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |