Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | GOT1 | P17174 | 1/20 | 0.30 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647751 | 0.86 | S1PR1 (0.44) | KMT2AS1PR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8766851 | 0.81 | S1PR1 (0.37) | KMT2AS1PR1RARARARBRARG | |
| SCHEMBL7683460 | 0.81 | RARA (0.44) | KMT2ANPC1RAB9ASMN1; SMN2RARA | |
| SCHEMBL7683467 | 0.80 | HDAC11 (0.36) | KMT2ARARARARBRARGMEN1 | |
| SCHEMBL8651356 | 0.78 | RARA (0.37) | KMT2AS1PR1RARARARBRARG | |
| SCHEMBL6621729 | 0.74 | HDAC11 (0.39) | KMT2AS1PR1SMN1; SMN2RARARARB | |
| SCHEMBL8765769 | 0.73 | S1PR1 (0.37) | KMT2AS1PR1SMN1; SMN2RARARARB | |
| SCHEMBL8796839 | 0.71 | PLA2G4A (0.42) | KMT2AS1PR1RARARARBRARG | |
| SCHEMBL13330393 | 0.71 | HTT (0.35) | KMT2ANPC1RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL8766824 | 0.71 | RARA (0.41) | KMT2ARARARARBRARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705167-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-06 | — | — | US | disclosed |