Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475729 | 0.88 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL6313692 | 0.78 | EDNRB (0.48) | EDNRAEDNRB | |
| SCHEMBL8713173 | 0.74 | KDM4E (0.46) | EDNRAEDNRB | |
| SCHEMBL7338764 | 0.74 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL8906392 | 0.74 | EDNRB (0.52) | EDNRAEDNRB | |
| SCHEMBL7337610 | 0.73 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL8277083 | 0.73 | ALDH1A1 (0.66) | — | |
| SCHEMBL8952113 | 0.72 | EDNRA (0.50) | EDNRAEDNRB | |
| Potassium SCHEMBL9263403 | 0.72 | EDNRB (0.57) | EDNRAEDNRB | |
| SCHEMBL9263398 | 0.72 | EDNRB (0.57) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821256-A | Endothelin receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-10-13 | — | — | US | disclosed |
| EP-0758650-A1 | Endothelin receptor antagonists | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |