Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27340180 | 0.88 | TSHR (0.50) | CYP3A4TSHRALDH1A1GAA | |
| SCHEMBL8650221 | 0.86 | MAPT (0.49) | L3MBTL1MAPTCRHBPCRHR2MAPK1 | |
| SCHEMBL7058019 | 0.85 | L3MBTL1 (0.62) | L3MBTL1MAPTCRHBPCRHR2MAPK1 | |
| SCHEMBL28900016 | 0.81 | L3MBTL1 (0.48) | L3MBTL1MAPTCRHBPCRHR2CYP3A4 | |
| SCHEMBL27583161 | 0.79 | MAPT (0.47) | L3MBTL1MAPTMAPK1CYP3A4TSHR | |
| SCHEMBL4656849 | 0.79 | ALDH1A1 (0.56) | L3MBTL1MAPTMAPK1CYP3A4TSHR | |
| SCHEMBL7061954 | 0.79 | L3MBTL1 (0.55) | L3MBTL1MAPTCRHBPCRHR2MAPK1 | |
| SCHEMBL18371949 | 0.78 | MAPT (0.46) | L3MBTL1MAPTCRHBPCRHR2MAPK1 | |
| SCHEMBL406358 | 0.78 | MAPT (0.51) | MAPTMAPK1CYP3A4TSHRMEN1 | |
| SCHEMBL27973235 | 0.77 | L3MBTL1 (0.66) | L3MBTL1MAPTCRHBPCRHR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719152-A | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0627434-A1 | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |