Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 3/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646454 | 0.91 | FDPS (0.44) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL8843563 | 0.87 | FDPS (0.42) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL8648798 | 0.87 | FDPS (0.55) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL8843664 | 0.79 | FDPS (0.47) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL8842723 | 0.76 | METAP1 (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8649526 | 0.74 | SLC6A1 (0.42) | MEN1ALOX15KMT2AGRIN2DGRIN3B | |
| SCHEMBL25254484 | 0.73 | FDPS (0.41) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL5329885 | 0.73 | FDPS (0.41) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL29039357 | 0.73 | FDPS (0.41) | FDPSMAPTMEN1MITFLMNA | |
| SCHEMBL27799803 | 0.72 | FDPS (0.40) | FDPSMAPTMEN1MITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703919-B1 | PHOSPHOSUCCINIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-09-02 | — | — | EP | claimed |
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |